An American actor, voice actor, writer and director. He is perhaps best known for his roles as Hal, the father in the Fox situation comedy "Malcolm in the Middle", and as Walter White in the AMC drama series Breaking Bad, for which he has won three consecutive Outstanding Lead Actor in a Drama Series Emmy Awards. Other notable roles include Dr. Tim Whatley on Seinfeld, Doug Heffernan's neighbor in The King of Queens, Astronaut Buzz Aldrin in From the Earth to the Moon, and Ted Mosby's boss on How I Met Your Mother.
| Movie | Chili Finger | 2027 | |
| Movie | When We Went MAD! | Self | 2025-06-24 |
| Movie | The Phoenician Scheme | Reagan | 2025-05-23 |
| Movie | Everything's Going to Be Great | Buddy Smart | 2025-06-20 |
| Movie | Argylle | Director Ritter | 2024-01-31 |
| Movie | Dinner Party Diaries with José Andrés | Self | 2024-03-18 |
| Movie | Kung Fu Panda 4 | Li (voice) | 2024-03-02 |
| Movie | The Tonight Show Starring Jimmy Fallon: 10th Anniversary Special | Self (archive footage) | 2024-05-14 |
| Movie | Asteroid City | 2023-06-08 | |
| Movie | Spider-Man: Across the Spider-Verse | Norman Osborn (voice) | 2023-05-31 |
| Movie | Jerry & Marge Go Large | Jerry Selbee | 2022-10-20 |
| Movie | Making of Better Call Saul: Finale | Self | 2022-09-01 |
| Movie | Show of Titles | "There's No Business Like Show Business" Performer | 2021-06-13 |
| Movie | An Audience with Adele | Self | 2021-11-21 |
| Movie | The Story of Soaps | Himself | 2020-05-19 |
| Movie | David Blaine: The Magic Way | Self | 2020-04-01 |
| Series | Home Movie: The Princess Bride | Count Tyrone Rugen | 2020-06-29 |
| Movie | The One and Only Ivan | Mack | 2020-08-21 |
| Series | Your Honor | 2020-12-06 | |
| Movie | The Upside | Phillip Lacasse | 2019-01-10 |
| Movie | The Road to El Camino: Behind the Scenes of El Camino: A Breaking Bad Movie | Self (extended version) | 2019-10-28 |
| Movie | El Camino: A Breaking Bad Movie | Walter White | 2019-10-11 |
| Movie | Godzilla: King of the Monsters | (archive footage) | 2019-05-29 |
| Movie | Every Act of Life | John Steinbeck (voice) | 2018-04-23 |
| Movie | Isle of Dogs | Chief (voice) | 2018-03-23 |
| Movie | Pink Elephants | Himself | 2018-11-15 |
| Movie | CinemAbility: The Art of Inclusion | Himself | 2018-10-05 |
| Movie | Power Rangers | Zordon | 2017-03-23 |
| Movie | The Disaster Artist | Himself (uncredited) | 2017-03-12 |
| Movie | Wakefield | Howard Wakefield | 2017-05-19 |
| Movie | The Words That Built America | Himself | 2017-07-04 |
| Movie | Last Flag Flying | Sal Nealon | 2017-11-03 |
| Movie | The Power of the Present | Himself | 2017-06-27 |
| Series | Philip K. Dick's Electric Dreams | Silas Herrick | 2017-09-17 |
| Series | Just For Laughs: Redux | 2017-07-01 | |
| Movie | Get a Job | Roger Davis | 2016-03-17 |
| Movie | Kung Fu Panda 3 | Li (voice) | 2016-01-23 |
| Movie | All the Way | Lyndon B. Johnson | 2016-05-23 |
| Movie | Why Him? | Ned Fleming | 2016-12-22 |
| Movie | The Infiltrator | Robert Mazur | 2016-07-13 |
| Movie | In Dubious Battle | Sheriff | 2016-10-08 |
| Series | Close Up with The Hollywood Reporter | Himself | 2015-08-02 |
| Series | Sneaky Pete | Vince | 2015-08-07 |
| Series | Hot Ones | Himself | 2015-03-12 |
| Series | The Late Show with Stephen Colbert | Himself | 2015-09-08 |
| Series | SuperMansion | Titanium Rex | 2015-10-08 |
| Movie | Trumbo | Dalton Trumbo | 2015-10-27 |
| Series | Last Week Tonight with John Oliver | Richard Sackler | 2014-04-27 |
| Movie | Godzilla | Joe Brody | 2014-05-14 |
| Movie | Sense of Smell | Tyler | 2014-06-27 |
| Movie | Interstellar | Walter "Walt" White / Heisenberg | 2014-11-05 |
| Movie | The Concert for Valor | Himself | 2014-11-11 |
| Movie | Cold Comes the Night | Topo | 2013-09-20 |
| Movie | Seth Rogen Is the Worst Person in the World | 2013-04-10 | |
| Movie | Übermansion | Titanium Rex | 2013-08-25 |
| Movie | Writer's Block | 2013-11-01 | |
| Movie | No Half Measures: Creating the Final Season of Breaking Bad | Himself | 2013-11-26 |
| Movie | David Blaine: Real or Magic | Himself | 2013-11-19 |
| Series | Big History | Narrator | 2013-11-02 |
| Movie | Red Tails | Colonel William Mortamus | 2012-01-19 |
| Movie | John Carter | Powell | 2012-03-07 |
| Movie | Madagascar 3: Europe's Most Wanted | Vitaly (voice) | 2012-06-06 |
| Movie | Argo | Jack O'Donnell | 2012-10-11 |
| Movie | Total Recall | Cohaagen | 2012-08-02 |
| Movie | Rock of Ages | Mayor Mike Whitmore | 2012-06-13 |
| Movie | Detachment | Richard Dearden | 2011-04-24 |
| Movie | The Lincoln Lawyer | Detective Lankford | 2011-03-17 |
| Movie | Leave | 2011-05-03 | |
| Movie | Batman: Year One | Jim Gordon (voice) | 2011-09-27 |
| Movie | Larry Crowne | Dean Tainot | 2011-06-30 |
| Movie | Contagion | Lyle Haggerty | 2011-09-08 |
| Movie | Drive | Shannon | 2011-09-15 |
| Movie | Love Ranch | James Pettis | 2010-06-30 |
| Series | Archer | Commander Tony Drake | 2009-09-17 |
| Series | Breaking Bad | Walter White | 2008-01-20 |
| Series | The Graham Norton Show | Himself | 2007-02-22 |
| Series | Fallen | Unknown | 2007-08-04 |
| Movie | Hard Four | Lt. Bryce Baxter | 2007-11-01 |
| Movie | Little Miss Sunshine | Stan Grossman | 2006-07-26 |
| Series | American Dad! | Unknown | 2005-02-06 |
| Series | How I Met Your Mother | Hammond Druthers | 2005-09-19 |
| Movie | Magnificent Desolation: Walking on the Moon | Buzz Aldrin (voice) | 2005-09-23 |
| Movie | Seeing Other People | 2004-05-07 | |
| Movie | Illusion | 2004-10-25 | |
| Series | Alf's Hit Talk Show | Unknown | 2004-07-07 |
| Series | The Tony Danza Show | Unknown | 2004-09-13 |
| Series | Jimmy Kimmel Live! | Unknown | 2003-01-26 |
| Movie | Holiday Reunion | Woodrow Snider | 2003-11-23 |
| Series | Real Time with Bill Maher | Himself | 2003-02-21 |
| Series | Lilo & Stitch: The Series | Mr. Jamieson (voice) | 2003-09-20 |
| Movie | The Santa Claus Brothers | Santa Claus (voice) | 2002-07-12 |
| Series | Gary & Mike | Unknown | 2001-01-12 |
| Series | Good Day Live | Unknown | 2001-09-17 |
| Movie | 'Twas the Night | Nick Wrigley | 2001-12-07 |
| Series | Malcolm in the Middle | Hal | 2000-01-09 |
| Movie | Terror Tract | 2000-10-18 | |
| Series | Curb Your Enthusiasm | Dr. Templeton | 2000-10-15 |
| Series | Family Guy | Unknown | 1999-01-31 |
| Movie | Last Chance | lance | 1999-01-01 |
| Series | Total Recall 2070 | Vilos Cohaagen | 1999-01-05 |
| Series | Pocket Dragon Adventures | 1998-01-01 | |
| Movie | Saving Private Ryan | War Department Colonel | 1998-07-24 |
| Series | From the Earth to the Moon | 1998-04-05 | |
| Series | The King of Queens | Tim | 1998-09-21 |
| Movie | Strategic Command | 1997-01-06 | |
| Movie | Time Under Fire | 1997-11-12 | |
| Series | The View | Unknown | 1997-08-11 |
| Series | Brooklyn South | Unknown | 1997-09-22 |
| Series | Goode Behavior | Unknown | 1996-08-26 |
| Movie | The Rockford Files: Punishment and Crime | Patrick Dougherty | 1996-09-18 |
| Movie | Armitage III: Poly Matrix | Eddie (voice) | 1996-06-25 |
| Series | The Louie Show | 1996-01-31 | |
| Movie | That Thing You Do! | Virgil "Gus" Grissom | 1996-10-04 |
| Series | The Pretender | Unknown | 1996-09-19 |
| Series | Sabrina, the Teenage Witch | Witch Lawyer | 1996-09-27 |
| Movie | Street Corner Justice | Father Brophy | 1996-09-27 |
| Movie | Kissing Miranda | Special Agent Falsey | 1995-02-25 |
| Series | Brotherly Love | Unknown | 1995-09-16 |
| Series | Armitage III | Eddie Borrows (voice) | 1995-02-25 |
| Series | MADtv | Unknown | 1995-10-14 |
| Movie | Clean Slate | Club Official | 1994-05-06 |
| Series | Babylon 5 | Ericsson | 1994-01-26 |
| Series | Chicago Hope | Unknown | 1994-09-18 |
| Movie | The Companion | Alan | 1994-10-14 |
| Series | Touched by an Angel | Unknown | 1994-09-21 |
| Movie | Erotique | 1994-05-14 | |
| Series | Walker, Texas Ranger | Unknown | 1993-04-21 |
| Movie | Prophet of Evil: The Ervil LeBaron Story | 1993-05-04 | |
| Series | Power Rangers | Twin Man | 1993-08-28 |
| Series | The X-Files | Unknown | 1993-09-10 |
| Movie | Dead Space | Dr. Frank Darden | 1991-10-21 |
| Movie | Dead Silence | Prof. Harris | 1991-08-26 |
| Series | The Flash | Philip Moses | 1990-09-20 |
| Movie | Corporate Affairs | 1990-10-05 | |
| Series | Seinfeld | Unknown | 1989-07-05 |
| Series | I Know My First Name Is Steven | Officer Dickenson | 1989-05-22 |
| Series | Baywatch | Tom Logan | 1989-04-23 |
| Series | Raising Miranda | 1988-11-05 | |
| Movie | The Big Turnaround | Jim | 1988-01-01 |
| Movie | The Return of the Six-Million-Dollar Man and the Bionic Woman | Dr. Shepherd | 1987-05-17 |
| Series | Jake and the Fatman | Unknown | 1987-09-26 |
| Movie | Amazon Women on the Moon | Paramedic #1 | 1987-09-18 |
| Series | Matlock | Unknown | 1986-03-03 |
| Series | L.A. Law | Unknown | 1986-09-15 |
| Series | North and South | Col. Austin | 1985-11-03 |
| Series | Murder, She Wrote | Unknown | 1984-09-30 |
| Series | Airwolf | Robert Hollis | 1984-01-22 |
| Series | Cover Up | Unknown | 1984-09-22 |
| Movie | Loving | Douglas Donovan | 1983-06-26 |
| Series | Hill Street Blues | Unknown | 1981-01-15 |
| Series | Falcon Crest | Unknown | 1981-12-04 |
| Movie | To Race the Wind | Quarterback (uncredited) | 1980-03-12 |
| Series | CHiPs | Unknown | 1977-09-15 |
| Series | The Emmy Awards | Unknown | 1949-01-25 |